在医学中，图像注册对于图像引导的干预措施和其他临床应用至关重要。但是，很难解决，通过机器学习的出现，最近在该领域的医疗图像注册方面已经取得了很大的进步。深度神经网络的实施为某些医学应用提供了机会，例如在更少的时间内进行图像注册，以高精度，在操作过程中对抗肿瘤中发挥关键作用。当前的研究对基于无监督的深神经网络的医学图像注册研究的最新文献进行了全面的范围审查，其中包括到本领域在此日期中发表的所有相关研究。在这里，我们试图总结医学领域中无监督的基于深度学习的注册方法的最新发展和应用。在当前的全面范围审查中，精心讨论和传达了基本和主要概念，技术，从不同观点，新颖性和未来方向的统计分析。此外，这篇评论希望帮助那些被这一领域铆接的活跃读者深入了解这一激动人心的领域。

We outline our work on evaluating robots that assist older adults by engaging with them through multiple modalities that include physical interaction. Our thesis is that to increase the effectiveness of assistive robots: 1) robots need to understand and effect multimodal actions, 2) robots should not only react to the human, they need to take the initiative and lead the task when it is necessary. We start by briefly introducing our proposed framework for multimodal interaction and then describe two different experiments with the actual robots. In the first experiment, a Baxter robot helps a human find and locate an object using the Multimodal Interaction Manager (MIM) framework. In the second experiment, a NAO robot is used in the same task, however, the roles of the robot and the human are reversed. We discuss the evaluation methods that were used in these experiments, including different metrics employed to characterize the performance of the robot in each case. We conclude by providing our perspective on the challenges and opportunities for the evaluation of assistive robots for older adults in realistic settings.

In post-covid19 world, radio frequency (RF)-based non-contact methods, e.g., software-defined radios (SDR)-based methods have emerged as promising candidates for intelligent remote sensing of human vitals, and could help in containment of contagious viruses like covid19. To this end, this work utilizes the universal software radio peripherals (USRP)-based SDRs along with classical machine learning (ML) methods to design a non-contact method to monitor different breathing abnormalities. Under our proposed method, a subject rests his/her hand on a table in between the transmit and receive antennas, while an orthogonal frequency division multiplexing (OFDM) signal passes through the hand. Subsequently, the receiver extracts the channel frequency response (basically, fine-grained wireless channel state information), and feeds it to various ML algorithms which eventually classify between different breathing abnormalities. Among all classifiers, linear SVM classifier resulted in a maximum accuracy of 88.1\%. To train the ML classifiers in a supervised manner, data was collected by doing real-time experiments on 4 subjects in a lab environment. For label generation purpose, the breathing of the subjects was classified into three classes: normal, fast, and slow breathing. Furthermore, in addition to our proposed method (where only a hand is exposed to RF signals), we also implemented and tested the state-of-the-art method (where full chest is exposed to RF radiation). The performance comparison of the two methods reveals a trade-off, i.e., the accuracy of our proposed method is slightly inferior but our method results in minimal body exposure to RF radiation, compared to the benchmark method.

The classification of sleep stages plays a crucial role in understanding and diagnosing sleep pathophysiology. Sleep stage scoring relies heavily on visual inspection by an expert that is time consuming and subjective procedure. Recently, deep learning neural network approaches have been leveraged to develop a generalized automated sleep staging and account for shifts in distributions that may be caused by inherent inter/intra-subject variability, heterogeneity across datasets, and different recording environments. However, these networks ignore the connections among brain regions, and disregard the sequential connections between temporally adjacent sleep epochs. To address these issues, this work proposes an adaptive product graph learning-based graph convolutional network, named ProductGraphSleepNet, for learning joint spatio-temporal graphs along with a bidirectional gated recurrent unit and a modified graph attention network to capture the attentive dynamics of sleep stage transitions. Evaluation on two public databases: the Montreal Archive of Sleep Studies (MASS) SS3; and the SleepEDF, which contain full night polysomnography recordings of 62 and 20 healthy subjects, respectively, demonstrates performance comparable to the state-of-the-art (Accuracy: 0.867;0.838, F1-score: 0.818;0.774 and Kappa: 0.802;0.775, on each database respectively). More importantly, the proposed network makes it possible for clinicians to comprehend and interpret the learned connectivity graphs for sleep stages.

Shape can specify key object constraints, yet existing text-to-image diffusion models ignore this cue and synthesize objects that are incorrectly scaled, cut off, or replaced with background content. We propose a training-free method, Shape-Guided Diffusion, which uses a novel Inside-Outside Attention mechanism to constrain the cross-attention (and self-attention) maps such that prompt tokens (and pixels) referring to the inside of the shape cannot attend outside the shape, and vice versa. To demonstrate the efficacy of our method, we propose a new image editing task where the model must replace an object specified by its mask and a text prompt. We curate a new ShapePrompts benchmark based on MS-COCO and achieve SOTA results in shape faithfulness, text alignment, and realism according to both quantitative metrics and human preferences. Our data and code will be made available at https://shape-guided-diffusion.github.io.

Sensor-based remote health monitoring is used in industrial, urban and healthcare settings to monitor ongoing operation of equipment and human health. An important aim is to intervene early if anomalous events or adverse health is detected. In the wild, these anomaly detection approaches are challenged by noise, label scarcity, high dimensionality, explainability and wide variability in operating environments. The Contextual Matrix Profile (CMP) is a configurable 2-dimensional version of the Matrix Profile (MP) that uses the distance matrix of all subsequences of a time series to discover patterns and anomalies. The CMP is shown to enhance the effectiveness of the MP and other SOTA methods at detecting, visualising and interpreting true anomalies in noisy real world data from different domains. It excels at zooming out and identifying temporal patterns at configurable time scales. However, the CMP does not address cross-sensor information, and cannot scale to high dimensional data. We propose a novel, self-supervised graph-based approach for temporal anomaly detection that works on context graphs generated from the CMP distance matrix. The learned graph embeddings encode the anomalous nature of a time context. In addition, we evaluate other graph outlier algorithms for the same task. Given our pipeline is modular, graph construction, generation of graph embeddings, and pattern recognition logic can all be chosen based on the specific pattern detection application. We verified the effectiveness of graph-based anomaly detection and compared it with the CMP and 3 state-of-the art methods on two real-world healthcare datasets with different anomalies. Our proposed method demonstrated better recall, alert rate and generalisability.

Pronoun resolution is a challenging subset of an essential field in natural language processing called coreference resolution. Coreference resolution is about finding all entities in the text that refers to the same real-world entity. This paper presents a hybrid model combining multiple rulebased sieves with a machine-learning sieve for pronouns. For this purpose, seven high-precision rule-based sieves are designed for the Persian language. Then, a random forest classifier links pronouns to the previous partial clusters. The presented method demonstrates exemplary performance using pipeline design and combining the advantages of machine learning and rulebased methods. This method has solved some challenges in end-to-end models. In this paper, the authors develop a Persian coreference corpus called Mehr in the form of 400 documents. This corpus fixes some weaknesses of the previous corpora in the Persian language. Finally, the efficiency of the presented system compared to the earlier model in Persian is reported by evaluating the proposed method on the Mehr and Uppsala test sets.

Coreference resolution (CR) is one of the most challenging areas of natural language processing. This task seeks to identify all textual references to the same real-world entity. Research in this field is divided into coreference resolution and anaphora resolution. Due to its application in textual comprehension and its utility in other tasks such as information extraction systems, document summarization, and machine translation, this field has attracted considerable interest. Consequently, it has a significant effect on the quality of these systems. This article reviews the existing corpora and evaluation metrics in this field. Then, an overview of the coreference algorithms, from rule-based methods to the latest deep learning techniques, is provided. Finally, coreference resolution and pronoun resolution systems in Persian are investigated.

在生物医学语料库中预先培训的语言模型，例如Biobert，最近在下游生物医学任务上显示出令人鼓舞的结果。另一方面，由于嵌入尺寸，隐藏尺寸和层数等因素，许多现有的预训练模型在资源密集型和计算上都是沉重的。自然语言处理（NLP）社区已经制定了许多策略来压缩这些模型，利用修剪，定量和知识蒸馏等技术，从而导致模型更快，更小，随后更易于使用。同样，在本文中，我们介绍了六种轻型模型，即Biodistilbert，Biotinybert，BioMobilebert，Distilbiobert，Tinybiobert和Cmpactactbiobert，并通过掩护的语言在PubMed DataSet上通过掩护数据进行了知识蒸馏而获得的知识蒸馏来获得。建模（MLM）目标。我们在三个生物医学任务上评估了所有模型，并将它们与Biobert-V1.1进行比较，以创建有效的轻量级模型，以与较大的对应物相同。所有模型将在我们的HuggingFace配置文件上公开可用，网址为https://huggingface.co/nlpie，用于运行实验的代码将在https://github.com/nlpie-research/compact-compact-biomedical-transformers上获得。

ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。